First-line Treatments for Clozapine-induced Drooling (Videos)

Drooling (sialorrhea) is one of the most common side effects of clozapine, and can be highly distressing and stigmatizing for some patients.  As for treatment options, the Clozapine Handbook recommends topical treatments, such as atropine or ipratropium bromide, as first-line treatments for clozapine-induced drooling.  View the below short videos sharing the proper way to optimally administer atropine drops and ipratropium bromide spray.

How to Self-Administer Atropine Drops for Drooling

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How to Self-Administer Ipratropium Bromide Spray for Drooling

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These videos discuss off-label use of particular medications. These off-label uses have not  necessarily been proven to be safe or effective for the indications discussed and are not approved for such uses by the Food and Drug Administration. This content is presented for informational purposes only and is not intended to endorse or promote use of these or any other medications. Off-label use of any medication is a clinical decision that must be made by a treating clinician in their professional judgment and with the patient’s informed consent. APA provides the information in this video on an “as is” basis and makes no warranty and assumes no responsibility regarding it. All individuals depicted in these videos are actors, not real patients.

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