What are the pros and cons of taking a long acting injectable antipsychotic medication?

Benefits of use of long acting injectable (LAI) antipsychotics: Increased adherence and steady plasma level balanced with decreased need to take daily oral doses; clinic visit or nursing visit for injection allows for consistent relationship and monitoring by clinicians. Disadvantages of use of LAI antipsychotics: Sometimes there is a slower titration period (however, newer formulations are bypassing or shortening this initial titration period); potential for pain at injection site; side effects may take longer to abate; clinic visit or nursing visit required for injection; historical perception of stigma may be associated with LAI antipsychotic medications, however,​ LAI formulations are being utilized to manage physical health conditions such as rheumatoid arthritis and osteoporosis, which may begin to lessen such stigma.

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