Are paliperidone (Invega) and risperidone (Risperdal) similar or different?

Paliperidone (Invega) is a metabolite of risperidone (Risperidone). While the efficacy and side effects of these medications are similar, there are some difference in 5-HT2A/D2 (serotonin/dopamine) binding ratios. The risperidone binding ratio is lower than the paliperidone binding ratio. More information is available here.

If you would like more information on this topic, or would like to provide any feedback, please send us a message using our consultation system. Be sure to let us know about which tip you are writing. We would love to hear from you, and the consultation system is free to use and confidential. Thank you!
Type: Knowledge Base
Answered by:
Alexander S. Young, MD, MSHS, SMI Physician Expert - University of California, Los Angeles
Date Answered: February 10, 2020
Topic: Psychopharmacology, 
Tags: Psychopharmacology,  Schizophrenia, 
  • Was this Helpful ?
  • YesNo
Ask an Expert

Join our #MissionForBetter now

Sign up for our newsletter. We’ll let you know about new resources, education, and more.

X