Talking to Individuals and Families About Clozapine

This resource was created by SMI Adviser content partners and approved by the SMI Adviser clinical expert team for inclusion in the knowledge base.

Clozapine, an antipsychotic or neuroleptic medication, is the only FDA-approved medication for treatment-resistant schizophrenia. Clozapine is also used to treat recurrent suicidal behavior in schizophrenia or schizoaffective disorder.

This fact sheet provides an overview of why someone might need clozapine, possible outcomes and side effects, and how to discuss clozapine with individuals and families.

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