There are not yet any tests that would predict for predisposition to bipolar disorder. Bipolar disorder does have some genetic risk established from twin studies (40-70% lifetime risk in monozygotic twins vs. 5% in dizygotic twins) compared to patterns in the general population (2% U.S. prevalence). There is not a single gene identified determining bipolar disorder, as several candidate genes have been positively identified and seem to be interactive in determining this genetic susceptibility (as well as the susceptibility of the psychopathology of other disorders). Additionally, epigenetic issues related to gene expression have been identified that contribute to the disease burden of bipolar disorder. For these reasons, there is not currently any testing that would reliably predict a genetic predisposition for bipolar disorder.