Detailed protocols for switching between LAIs have not all been established, and this is true for risperidone microspheres LAI (Risperdal Consta) as well. For an overview, see the guidance for using Risperdal Consta.
Establish tolerability to risperidone. Plan to administer the first dose of Risperdal Consta three weeks prior to the next scheduled injection of the original LAI. Risperdal Consta will not be at steady state for three weeks following the initial injection.
When thinking about the dose of the new LAI (here Risperdal Consta), refer to the conversion table for approximate equivalent doses. Risperdal Consta is available in 12.5 mg, 25 mg, 37.5 mg, and 50 mg strengths.
FDA medication label
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