Leveraging mobile-first technologies and adopting a consumer mentality approach to healthcare will be the deciding factor in creating health interventions this century. Recent advances in digital health have yielded novel means to manage and treat medical conditions across multiple health specialties. Widespread adoption of technology in daily lives coupled with health analytics will also yield new pathways to develop mental health insights based on behavior and actions from real-world evidence. This, in turn, will spur creative methods of treatment across both traditional biopharma and novel startups in disease treatment innovation. Such examples currently under development include smart combination medications, digital biomarkers, and digital therapeutics. This presentation will evaluate the current adoption and utilization of such devices and technology and identify other technologies currently under investigation.