Overweight and obesity in persons living with serious mental illness are highly prevalent and a leading cause of preventable death through their effects on other cardiovascular disease risk factors and cardiovascular disease. Some psychotropic medications contribute to weight gain. However, evidence-based interventions exist and have shown that persons living with serious mental illness can successfully lose weight. Simple messaging and repetition of key lifestyle behavior challenges (e.g., saying no to sugar drinks and junk food, eating more vegetables, and exercising dally) are helpful strategies.  Monitoring these behaviors and setting short-term behavioral goals can increase accountability and success.