Chronic pain is a very common condition affecting up to 20% of adult population. Studies indicate that chronic pain often co-occurs with psychiatric illnesses, including depression, anxiety , and SMI. Data also indicate that this co-occurrence leads to a number of worsened outcomes. This webinar will use a de-identified case to illustrate the relevant topic. The webinar will first introduce the case. It will then go into some of the data showing co-morbidity, as well as outcomes related to co-morbid pain and mental illnesses. Next, the webinar will explore bio-psychosocial models that may explain this co-occurrence. Finally, the webinar will lay out an approach to appropriate diagnosis and management of the patient with co-occurring chronic pain and SMI. The management recommendations will begin with psychosocial, will then go into pharmacological, and end with exploratory ideas. Throughout this content, webinar will emphasize effective communication strategies with the patient. The webinar will return to the de-identified case periodically to better illustrate these concepts.